Wrinkles are lines and creases that form as part of ageing.
As people get older, their skin becomes drier, thinner, less elastic and less able to protect itself from damage, with less fat.
Faint wrinkles can become deep furrows or crevices over time. Grooves form under the skin during facial expressions. Young flexible skin springs back into place, but as skin ages, it loses its flexibility and springing back becomes harder and less frequent, resulting in permanent grooves.
Ultraviolet light exposure and smoking accelerate wrinkle formation and the ageing process.
Wrinkles can be divided into
Winkles that we've treated frequently:
Neurotoxin injection for treatment of facial wrinkles is one of the most frequently performed cosmetic procedures. Neurotoxins inhibit release of acetylcholine at the neuromuscular junction. Treatment of specific overactive muscles causes localized muscle relaxation that smoothens the overlying skin and reduces wrinkles.
Injectable dermal fillers are intended to fill in the lost volume in wrinkles, giving a smoother appearance. Most fillers are temporary and are eventually absorbed into the body. Temporary fillers can be classified into 2 broad groups:
Fillers can be injected directly into deeper lines. They can also be injected more superficially using an injector gun to hydrate the skin and ameliorate fine lines (Hydrashine / Skinboosters).
Deep facial lines may be tethered down to the deeper structures such as the superficial musculoaponeurotic system (SMAS) or bone. In subdermal incision (subcision), surgical tools inserted under the skin via small needle punctures are used to release the tethering of the wrinkles to the deeper layers.
Filler is then interposed to prevent the two layers from sticking back together during the healing process.
Fractional laser resurfacing involves the deposition of a pixelated pattern of microscopic laser wounds surrounded by healthy tissue resulting in both greater efficacy and shorter downtime compared to non-fractionated treatments. It can be further subdivided into ablative and non-ablative. Ablative fractional lasers have longer wavelengths (e.g. CO2 10600nm) and lead to full-thickness destruction of skin, whereas non-ablative fractional lasers have shorter wavelengths (e.g. Erbium Glass 1550nm) and leave an intact skin surface. CO2 has greater efficacy compared with Erbium Glass but longer recovery time and a higher risk of complications.
Fractional Infrared Lasers have a good body of research evidence demonstrating safety and efficacy.
Discovery Pico Plus is a second-generation triple wavelength picosecond laser that generates the highest peak power in the world. A special microlens array further focusses the energy into numerous micro-beams 2mm under the skin. The highly concentrated energy produces laser-induced optical breakdown (LIOB) stimulating collagen production with almost no downtime.
Fractional Radiofrequency creates a pyramidal thermal injury zone (a relatively large coagulation zone deep in the skin with minimal surface damage) as opposed to the columnar shape of ablative lasers. Hence Fractional Radiofrequency has a favourable side-effect profile (such as downtime, post-inflammatory hyperpigmentation) in comparison to fractional lasers.
Skin remodelling requires heat delivery to the deep part of the skin. However, in most machine-based treatments for scarring such as lasers, much of the energy is dissipated at the skin surface and little reaches the deep layers. Fractional microneedle radiofrequency overcomes this using insulated microneedles to spare the upper part of the skin and deliver radiofrequency energy precisely up to 4mm deep in the skin, resulting in faster recovery, higher efficacy and increased safety.
Topical medications such as peptides, retinoids, hydroxy acids and antioxidants may help prevent and improve wrinkling and other signs of ageing. They tend not to work so well for deep wrinkles.
Dr Wan believes in a tailored combination approach using all the tools available:
Wrinkles with a dynamic component should have neurotoxins wherever feasible. This will help to smoothen out the wrinkle and prevent it from getting worse. Long-term treatment with neurotoxins can actually prevent the development of imprinted facial lines, so Dr Wan prefers to initiate treatment early rather than wait for the wrinkles to progress into static lines. Dr Wan prefers to initiate treatment at a lower dosage of toxin and aim for a natural reduction rather than the total elimination of wrinkles.
These help to build up collagen and tighten the skin. The choice of which treatment to use depends on:
These usually give rapid improvement for depressed, static wrinkles. Rheology of filler should be appropriate for the wrinkle (e.g. hydrashine / skinboosters for very fine wrinkles vs harder, longer-lasting fillers for deep glabellar troughs). Subcision is indicated to lift deeply tethered wrinkles first before filler.
Helps to potentiate the effect of energy devices and maintain collagen stimulation
FOUNDER / MEDICAL DIRECTOR
Wrinkling appears around the eyes, mouth and forehead due to repeated underlying muscle action resulting in permanent changes to underlying tissues, progressing from fine dynamic wrinkles initially to deep static wrinkles over time. Sagging occurs due to a relative skin excess, lack of elastic recoil as well as fat accumulation.
Fractional Energy Devices tighten skin, improving wrinkles. The choice of which device would depend on the relatively thickness of the skin and wrinkles. The availability of multiple fractional devices allows Dr Wan to choose the most suitable and effective one for the clinical scenario.
HIFU with shallow depth cartridges such as 1.5mm or 2mm tighten skin, but Fractional Energy Devices may be more cost-effective especially for fine wrinkles in small areas of thin skin, like the eyelids and area around the lips where it can be difficult to position the HIFU applicator and even 1.5mm may be too deep.
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