Cultures and societies worldwide associate luxurious hair with youth, beauty, and good health. Hair has always been one of the most important aspects of a person’s aesthetics and personality. People express themselves through hairstyles of all sorts and for many, their hair is what makes them feel beautiful.
To many people, the mention of hair conjures up images of ladies with magnificent, flowing locks. Many women associate their hair with their sexuality, sensuality, and beauty and may feel that they are no longer attractive due to hair loss or thinning hair
Hair has also been associated with power since biblical times. To men, their hair is a key part of the male psyche that represents their virility, and hair loss, a bald spot, or thinning hair may lead them to feel less manly or attractive.
Usually thought of as something men start worrying about as they get older, hair loss (often extensive and sudden) can impact on anyone – male or female – at any time. Hair thinning or baldness are serious concerns and can be devastating to self-esteem.
These topical medications promote increased growth of healthy eyelashes, eyebrows and adnexal hairs.
Interact with hair follicle prostanoid receptors, stimulating resting follicles (telogen phase) to transition to growing follicles (anagen phase).
Prolong the anagen phase of eyelashes, leading to an increase of eyelash length.
Has also been studied in alopecia such as alopecia areata and androgenic alopecia.
The efficacy of low-level light/laser therapy (LLLT) was discovered by chance when mice irradiated with a low fluence red laser had increased hair growth. The exact mechanism is still unknown but LLLT may increase anagen hairs through the release of nitric oxide and reduced inflammation.
Fractional laser resurfacing involves the deposition of a pixelated pattern of microscopic laser wounds surrounded by healthy tissue resulting in both greater efficacy and shorter downtime compared to non-fractionated treatments. Fractional lasers induce hair growth by efficiently penetrating the scalp and upregulating the Wnt/β-catenin pathways.
Fractional laser therapy may not only treats alopecia but may also prevent recurrent hair loss. Trauma stimulated wound healing likely plays a role. Hair follicle stem cells provide progeny that migrate to the epidermal defect and promote re-epithelialization. This cutaneous wound healing process increases tremendously during the anagen stage of the hair cycle, and additional hair follicles regrow after wounding.
Regenera Activa is a medical device that processes tiny samples of scalp skin to extract hair follicle progenitor cells, separating them into smaller, more absorbable autologous micrografts. The cell suspension is then infiltrated into areas of hair loss to help damaged hair follicles regenerate.
Regenera Activa has been studied to improve hair density, hair counts and scalp coverage in patients with androgenic alopecia. Reduction of hair loss is first witnessed, usually after 1 to 3 months, followed by the improved thickness and density of existing hair and growth of new hair over the next 6 months. Results may last from 1 to 3 years.
Hair transplantation involves the relocation of skin plugs with healthy hair follicles to bald areas. Depending on the area of hair loss, several hundred to thousand plugs may be required
In Dr Wan’s view, it is important to first assess the patient in detail to arrive at an accurate diagnosis, looking out in particular for medical conditions that could be causing hair loss.
While non-invasive treatments such as medications and LLLT may be slow to show effect, patients may not be ready to undergo costly hair transplants that may not always be successful. Hair biology is complex and hair loss is a complicated multifactorial condition. In Dr Wan’s opinion a multimodal approach should be instituted to tackle the hair loss process from all angles, thus he usually uses combination treatment for a synergistic effect. For example:
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